Evaluation of Miconazole Therapy in Experimental Disseminated Candidiasis in Laboratory Rats
نویسندگان
چکیده
منابع مشابه
Evaluation of miconazole therapy in experimental disseminated candidiasis in laboratory rats.
Miconazole, a broad-spectrum antimycotic agent with some antibacterial activity, has recently become available for experimental parenteral use in the United States. Its efficacy as an anticandidal drug was tested in adult Wistar rats. A previously established infectious dose of 5 x 10(6)Candida albicans was intravenously injected into 250- to 300-g animals. This dose was fatal to 95% (20/21) of...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1978
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.13.2.321